Myotonia and Muscle Stiffness in NMD
study id #: NCT04411732
condition: Neuromuscular Disorders
status: Recruiting
purpose:The primary objective of this study is to assess stiffness, muscle tone, relaxation periods and elasticity of various muscles in patients with dystrophic or non-dystrophic myotonia. The secondary objectives are (1) to provide reference values for stiffness, muscle tone, relaxation periods and elasticity of various muscles in patients with dystrophic or non-dystrophic myotonia; to provide reference values for stiffness, muscle tone, relaxation periods and elasticity of various muscles in patients with non-myotonic neuromuscular disorders, (3) assess correlations between to compare result values for stiffness, muscle tone, relaxation periods and elasticity with clinical muscle function tests, measured by clinical evaluation (MRC-scale) and the 6-minute walk test; (4) assess correlations between subcutaneous fat and muscle thickness and echogenicity, measured by muscle ultrasound and result values for stiffness, muscle tone, relaxation periods and elasticity.
intervention: MyotonPro, Six-minute walk test, Semiquantitative muscle ultrasound, Hand-held Dynamometry of muscle strength
results: https://clinicaltrials.gov/ct2/show/results/NCT04411732
last updated: February 04, 2022
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